Although nobody seems sure of the origins of the drink, it first appeared in 1973 when drinkers who consumed a glass of Champagne or beer that contained the toe could then declare themselves true "sourtoers."
Today, the toe can be placed in any drink but one rule still applies: "You can drink it fast, you can drink it slow -- but the lips have gotta touch the toe."
Some 60,000 people have reportedly tried the Sourtoe cocktail to date.
Sourtoe Cocktail Club, Downtown Hotel, Dawson City, Yukon; Sourtoe Cocktail: $5.80
The Rum Blazer
Jerry "The Professor" Thomas was an American bartender who's considered the father of American mixology.
Thomas perfected the technique of lighting whisky and throwing the flaming liquid between two silver tankards.
The late bartender inspired Shaka Zulu's Rum Blazer: a fiery concoction prepared at the customer's table and only served at a temperature below 50°F/10°C.
It contains spiced rum, Grand Marnier Liqueur and cinnamon dust and was inspired by the famous Blue Blazer cocktail.
Shaka Zulu, London, UK; +44 0203 376 9911; The Rum Blazer: $17
This Guy Fawkes-inspired cocktail is the creation of Sydney bartender Grant Collins, whose favorite ingredients include dry ice, liquid nitrogen and jelly.
Previous creations have included the Bacon and Maple Syrup Manhattan and the La Premiere, which blends Appleton Rum with popcorn.
"For the Gunpowder Plot, we infuse gin with gunpowder flavors and shake it with fernet branca (a traditional herbal digestive) and egg white," explains Colin Tam, head bartender.
"This method leaves the cocktail with a thick layer of froth on the top. When the cloche is closed and smoke is added the froth is infused with a smoky, wooden flavor which changes the drink completely."
It contains gunpowder-infused gin, spiced gunpowder syrup and bitters and comes served in a smoking cloche amidst a pile of twigs and oak-scented fog.
Zeta Bar, Level 4, 488 George Street, Sydney, NSW 2000; +61 02 9265 8374; Gunpowder Plot: $20
Drinking a cocktail out of a toilet bowl might not seem like the classiest way to start the night, but they go down a treat at Rock and Rita's in Las Vegas.
The calorie-filled Crapper is a chocolate-based Piña Colada garnished with a Snickers bar. You get to keep the glass once done.
Rock and Rita's, Circus Circus Hotel & Casino, 2880 Las Vegas Blvd S, Las Vegas, USA; +1 702 691 5991; The Crapper: $25
Diamonds are Forever
Only the finest ingredients go into this luxurious $1,347 cocktail: L'Heraud Grand Champagne Cognac, Luxor 24k Gold Flake Champagne and The Bitter Truth Jerry Thomas bitters.
Served in a Swarovski Crystalline Cocktail Glass, which contains diamonds in the stem and which you get to keep, it was inspired by the Junsui Lounge in the Burj Al Arab, which features 29,000 Swarovski crystals.
Skyview Bar, 27th Floor, Burj Al Arab, Dubai, United Arab Emirates; +971 4 301 7600; Diamonds are Forever: $1,347