Crews are busy cleaning up a hazardous material spill in Monroe County that has closed parts of Interstate 80 and Route 33.

State police from Swiftwater are investigating the spill from a commercial vehicle that happened around 11 a.m. Thursday.

The spill occurred on I-80 westbound at Route 715, between mile markers 302 and 298.

Motorists are advised to avoid the area, because  the spill has created massive traffic tie-ups.

Police recommend drivers going north from the Lehigh Valley area should take Route 22 west, then go north on the Pennsylvania Turnpike to bypass the congestion,  which has required closing a northern section of Route 33.

"Multiple agencies are working to open the interstate," stated state police in a news release.

County officials said liquid pesticide  spilled onto I-80 in Hamilton and Pocono townships.

Police have evacuated a 150-foot perimeter around the spill until it's cleaned up.

No injuries were reported.

At 11:21 a.m. Thursday, the Monroe County Control Center received a report of a tractor-trailer leaking an unknown substance on I-80 westbound at the Exit 299 off ramp.

I-80 eastbound initially was closed from the junction at I-380 to Bartonsville, and westbound from Bartonsville to mile marker 298.

By 3:15 p.m., I-80 east had reopened, but northbound Route 33 was closed between mile markers 25 and 28, reported the Monroe County Communications Center.

I-80 west remain closed.

Traffic was being diverted onto Route 209 at Route 33's mile marker 25, sending people to I-80 east.

That section of Route 33 was closed because emergency officials don't want people going onto I- 80 or Route 611, saying they already have major traffic back-ups  in the area.

Officials were not sure when the hazardous materials would be cleaned up and the highways reopened.

Local traffic is advised to take Route 611 north to Route 715 south and continue west on Sullivan Trail to reach I-80 west.