Bryant kicked field goals of 29 and 30 on the next two drives.
The Eagles made it 30-17 on Vick's 7-yard TD pass to McCoy in the fourth quarter.
Samuel had 25 interceptions and went to three Pro Bowls in four seasons in Philadelphia before the acquisitions of Asomugha and Rodgers-Cromartie forced him out.
He was traded to the Falcons for a seventh-round pick in April and enjoyed his return to Lincoln Financial Field.
"I love the fans," he said. "They can boo me. They can cheer for me. Doesn't do anything but add fuel to the fire."