Jesse Biddle returned from a hail-induced head injury on Saturday in the Fightin Phils 3-2 loss to the SeaWolves in Erie.
Biddle (3-5, 3.14) gave up three runs and pitched into the seventh inning, suffering the loss on the mound for Reading.
Biddle had missed his last start after he was hit in the head by ice during a hailstorm, leaving him with a concussion.
Albert Cartwright homered in a losing effort for the Fightin Phils.
Reading (29-24) has now lost five of six, and will look to avoid the sweep in Erie in its series finale on Sunday at 1:35pm.